Chemotherapy for thymic carcinoma in an adult patient with HIV infection

被引：0

作者：

Iriki, Toyohisa ^{[1
,2
]}

Ishii, Satoru ^{[1
]}

Takeda, Yuichiro ^{[1
]}

Nishijima, Takeshi ^{[3
]}

Teruya, Katsuji ^{[3
]}

Oka, Shinichi ^{[3
]}

Mochizuki, Makoto ^{[4
]}

Sugiyama, Haruhito ^{[1
]}

Kobayashi, Nobuyuki ^{[1
]}

机构：

[1] Natl Ctr Global Hlth & Med, Dept Resp Med, Shinjuku Ku, Tokyo 1628655, Japan

[2] Kumamoto Reg Med Ctr, Div Resp Dis, 5-16-10 Honjo, Kumamoto 8600811, Japan

[3] Natl Ctr Global Hlth & Med, AIDS Clin Ctr, Shinjuku Ku, Tokyo 1628655, Japan

[4] Natl Ctr Global Hlth & Med, Dept Pathol, Shinjuku Ku, Tokyo 1628655, Japan

来源：

INTERNATIONAL CANCER CONFERENCE JOURNAL | 2012年 / 1卷 / 03期

关键词：

Thymic carcinoma; ADOC chemotherapy; HIV infection; HAART; Cytochrome;

D O I：

10.1007/s13691-012-0027-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 69-year-old man was referred to our hospital in June 2010 after the diagnosis of an anterior mediastinal tumor and HIV infection. Histopathological examination of a CT-guided needle biopsy specimen showed undifferentiated thymic carcinoma. Chest CT revealed pleural dissemination, bone invasion, and left lung metastases. The final diagnosis was Masaoka stage IVb. Surgery was considered inappropriate. Instead, the patient first underwent highly active antiretroviral therapy for HIV infection, followed by four courses of cisplatin, doxorubicin, vincristine, and cyclophosphamide chemotherapy for thymic carcinoma. A partial response was achieved. To our knowledge, this is the first report of thymic carcinoma in an adult patient with HIV infection.

引用

页码：142 / 146

页数：5

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