DELAYED WALLERIAN DEGENERATION IN SCIATIC-NERVES OF C57BL/OLA MICE IS ASSOCIATED WITH IMPAIRED REGENERATION OF SENSORY AXONS

被引：111
|
作者：
BISBY, MA
CHEN, S
机构：
[1] Department of Physiology, Queen's University, Kingston, Ont.
来源：
BRAIN RESEARCH | 1990年 / 530卷 / 01期
关键词：
C57BL/Ola mouse; Regeneration; Sensory axon; W#allerian degeneration;
D O I：
10.1016/0006-8993(90)90666-Y
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Wallerian degeneration is delayed following sciatic nerve crush in C57BL/Ola mice. Compared to C57BL/6J mice, regeneration of sensory axons is significantly slowed in the Ola mice, but reinnervation does eventually occur. We conclude that Wallerian degeneration is a prerequisite for normal sensory axon regeneration following a crush injury to peripheral nerve. © 1990.
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页码：117 / 120
页数：4
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