SIMULATION OF OZONE UPTAKE DISTRIBUTION IN THE HUMAN AIRWAYS BY ORTHOGONAL COLLOCATION ON FINITE-ELEMENTS

被引:16
|
作者
HU, SC [1 ]
BENJEBRIA, A [1 ]
ULTMAN, JS [1 ]
机构
[1] UNIV BORDEAUX 2,PHYSIOL LAB,F-33076 BORDEAUX,FRANCE
来源
COMPUTERS AND BIOMEDICAL RESEARCH | 1992年 / 25卷 / 03期
关键词
D O I
10.1016/0010-4809(92)90042-9
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Ozone transport in a rigid single-pathway anatomic model of the lung was analyzed by a stable convergent numerical algorithm, the method of orthogonal collocation on finite elements. The simulations predicted the dynamic behavior of gas phase concentration profiles for both ozone and an insoluble inert gas. An internal quasi-stationary diffusion front was observed during early inspiration for both gases. In addition, the absorptive distribution of ozone in lung airways was computed as a total dose as well as a tissue dose. The total dose of ozone decreased along the airway path from the mouth. However, the tissue dose of ozone increased along the conducting airways, reached a maximal dose in the terminal bronchioles, and decreased sharply in the respiratory airways. © 1992.
引用
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页码:264 / 278
页数:15
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