RAT-BRAIN ENDOGENOUS MAO INHIBITOR (TRIBULIN) ACTIVITY DURING CARRAGEENAN-INDUCED ACUTE PAW INFLAMMATION

被引：3
|
作者：
BHATTACHARYA, SK
TRIPATHI, M
ACHARYA, SB
机构：
[1] Neuropharmacology Laboratory, Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi
来源：
JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION | 1991年 / 84卷 / 1-2期
关键词：
TRIBULIN; CARRAGEENAN INFLAMMATION; STRESS;
D O I：
10.1007/BF01249117
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The endogenous monoamine oxidase (MAO) inhibitor (tribulin) activity of rat brain was investigated during the course of carrageenan induced acute paw inflammation. The increase in rat brain tribulin activity closely paralleled the time course intensity of the inflammation. The study indicates that, like externally induced stress, internal stress caused by the inflammation induced hyperalgesia can also induced augmented brain tribulin activity. The findings, thus, support the hypothesis that tribulin may function as an endogenous endocoid marker of stress.
引用
收藏
页码：135 / 140
页数：6
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