VIRULENCE IN ACTINOBACILLUS-PLEUROPNEUMONIAE AND RTX TOXINS

被引：218
|
作者：
FREY, J [1 ]
机构：
[1] UNIV BERN,INST VET BACTERIOL,CH-3012 BERN,SWITZERLAND
来源：
TRENDS IN MICROBIOLOGY | 1995年 / 3卷 / 07期
关键词：
D O I：
10.1016/S0966-842X(00)88939-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
RTX toxins are pore-forming, cytolytic protein toxins that occur widely among pathogenic Gram-negative bacteria. RTX toxins appear to play a direct role in the virulence of Actinobacillus pleuropneumoniae, the etiological agent of porcine pleuropneumonia. This discovery has led to the development of new diagnostic and epidemiological tools, as well as vaccines, that are useful for a broad variety of serotypes.
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页码：257 / 261
页数：5
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