AMINOALKYLSULFONIC ACID-DERIVATIVES - SYNTHESIS AND ANTIVIRAL ACTIVITY

被引：0
|
作者：
BADEEV, YV
KOROBKOVA, VD
IVANOV, VB
POZDEEV, OK
GILMANOVA, GK
BATYEVA, ES
ANDREEV, SV
机构：
来源：
KHIMIKO-FARMATSEVTICHESKII ZHURNAL | 1991年 / 25卷 / 04期
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中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Interaction of aminosulfinic and carbonylic acids yielded alpha-aminoalkylsulfonic acid derivatives which were investigated for a tiviral activity. They were found to have pronounced antiviral properties against various influenza A virus strains (H3N2) in vitro and in vivo. With experimental influenza infection, one of the possible mechanisms of antiviral action may be due to their effects on the immune system. alpha-Aminoalkylsulfonic acid derivatives were ascertained to show an immunostimulating effect in a primary response to a thymus-dependent antigen (sheep erythrocytes).
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页码：43 / 45
页数：3
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