MITOGENIC AND COLONY-STIMULATING FACTOR-INDUCING ACTIVITIES OF POLYSACCHARIDE FRACTIONS FROM THE FRUIT BODIES OF DICTYOPHORA-INDUSIATA FISCH

被引:0
|
作者
HARA, C
KUMAZAWA, Y
INAGAKI, K
KANEKO, M
KIHO, T
UKAI, S
机构
[1] KITASATO UNIV, SCH PHARMACEUT SCI, MINATO KU, TOKYO 108, JAPAN
[2] GIFU PHARMACEUT UNIV, GIFU 502, JAPAN
关键词
POLYSACCHARIDE; DICTYOPHORA-INDUSIATA; MITOGENIC ACTIVITY; COLONY-STIMULATING FACTOR-INDUCING ACTIVITY; ACETYLATED (1-]3)-ALPHA-D-MANNAN; BRANCHED (1-]3)-BETA-D-GLUCAN; FUCOMANNOGALACTAN;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Biological effects (mitogenic and colony-stimulating factor (CSF)-inducing activities) of five homogeneous polysaccharides and a conjugated polysaccharide fraction isolated from the fruit bodies of Dictyophora indusiata FISCH. were investigated. Fucomannogalactan (T-3-Ad) and conjugated polysaccharide fraction (T-2-A) exhibited significant mitogenic and CSF-inducing activities. Among two beta-(1 --> 6)-branched (1 --> 3)-beta-D-glucans (T-4-N and T-5-N), only T-4-N showed both mitogenic and CSF-inducing effects. Partially O-acetylated (1 --> 3)-alpha-D-mannans (T-2-HN and T-3-M') did not show these effects.
引用
收藏
页码:1615 / 1616
页数:2
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