MAST-CELLS FROM HUMAN GASTRIC-MUCOSA - A COMPARATIVE-STUDY WITH LUNG AND COLONIC MAST-CELLS

被引：6
|
作者：
LIU, WL
BOULOS, PB
LAU, HYA
PEARCE, FL
机构：
[1] UNIV LONDON UNIV COLL,DEPT CHEM,LONDON WC1E 6BT,ENGLAND
[2] UNIV LONDON UNIV COLL,DEPT SURG,LONDON WC1E 6BT,ENGLAND
来源：
AGENTS AND ACTIONS | 1991年 / 33卷 / 1-2期
基金：
英国惠康基金;
关键词：
D O I：
10.1007/BF01993114
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Mast cells isolated from human gastric mucosa released histamine on challenge with IgE-directed ligands and calcium ionophores but were esentially unresponsive to a variety of non-immunological stimuli. Moreover, immunologically induced histamine secretion from these cells was inhibited by a number of anti-allergic agents including anti-asthmatic chromones, beta-adrenoceptor agonists and phosphodiesterase inhibitors. In total, these data indicate that mast cells from the human gastric mucosa are in many respects functionally similar to their lung and colonic counterparts.
引用
收藏
页码：13 / 15
页数：3
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