SYNTHESIS AND ANTIFUNGAL ACTIVITY OF NOVEL 1,2,4-TRIAZOLE DERIVATIVES

被引：0

作者：

Yashaswini, K. ^{[1
]}

Revanasiddappa, B. C. ^{[1
]}

Kumar, M. Vijay ^{[1
]}

Kumar, Hemanth ^{[1
]}

机构：

[1] Nitte Deemed Be Univ, NGSM Inst Pharmaceut Sci, Dept Pharmaceut Chem, Mangalore 575018, Karnataka, India

来源：

HETEROCYCLIC LETTERS | 2018年 / 8卷 / 03期

关键词：

Methyl paraben; Potassium dithiocarbazinate salt; 1,2,4-triazole; antifungal activity;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 4-amino-3-mercapto-1,2,4-triazole (1) with appropriately N-substituted-achloroacetanilides (2) in aq. potassium hydroxide yielded corresponding 2-(4-amino-5-(4hydroxyphenyl)-4H-1,2,4--triazol-3-ylthio)-N-phenylacetamides(3a-j). All the new compounds were evaluated for In-vitro antifungal activity. The newly synthesized compounds were assigned on the basis of H-1-NMR, IR and Mass spectral data.

引用

页码：613 / 617

页数：5

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