DETERMINATION OF THE BIOLOGICAL-ACTIVITY OF CHALONE-CONTAINING PREPARATION FROM EHRLICH ASCITIC CARCINOMA AND ITS FRACTIONS OBTAINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY IN A CELL-CULTURE DERIVED FROM THIS TUMOR

被引：1
|
作者：
GEMBITSKII, DS [1 ]
KARPETS, LZ [1 ]
ADRIANOV, NV [1 ]
ANOKHIN, AI [1 ]
ROMANOV, YA [1 ]
机构：
[1] RUSSIAN MED UNIV,ECOL TOXICOL & METAB DRUGS LAB,MOSCOW,RUSSIA
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1994年 / 117卷 / 01期
关键词：
EHRLICH ASCITIC CARCINOMA; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; CHALONE; DNA SYNTHESIS;
D O I：
10.1007/BF02444088
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
It is shown that cultured Ehrlich ascitic carcinoma cells are a convenient test system for the investigation of the effects of various factors on DNA synthesis in the cells of this tumor. The application of this system markedly facilitates fractionation of a chalone-containing preparation, the purpose of this fractionation being the isolation of components affecting specific phases of the mitotic cycle.
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页码：83 / 86
页数：4
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