VITAMIN-E ADJUVANT FORMULATIONS IN MICE

被引：23
|
作者：
TENGERDY, RP
LACETERA, NG
机构：
[1] Department of Microbiology, Colorado State University, Fort Collins
来源：
VACCINE | 1991年 / 9卷 / 03期
关键词：
VITAMIN-E; ADJUVANTS; HUMORAL AND CELL-MEDIATED IMMUNITY;
D O I：
10.1016/0264-410X(91)90155-Y
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Water-in-oil-type adjuvants prepared with natural or synthetic vitamin E as the oil phase, Arlacel A or Montanide 103 as emulsifier and 1.0% aqueous solution of bovine serum albumin (BSA) as antigen were tested in mice. An emulsion of 0.42 ml vitamin E, 0.42 ml special mineral oil, 0.15 ml Arlacel A and 1.0 ml BSA gave maximal humoral response, but 0.85 ml special mineral oil, 0.15 ml Arlacel A and 1.0 ml BSA (standard Freund's incomplete adjuvant formulation) gave the greatest delayed-type hypersensitivity response.
引用
收藏
页码：204 / 206
页数：3
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