Vitalmicroscopic findings confirm the existence of an organized prelymphatic system favoring the fluid and substance drainage by the initial lymphatics. By means of open connections of solphasic tissue channels with the initial lymphatics - together with the system of open junctions - the contribution to the maintenance of the interstitial fluid balance is essentially increased. In connection with the permeability for fluid and proteins of the capillary bed itself this contribution appears important. The transinterstitial fluid transport is favored additionally by the fluid movement along the connective tissue fibres.