SYNERGISTIC EXTRACTION OF PENICILLIN-G WITH ALIPHATIC-ALCOHOLS AND BUTYL ACETATE

被引：6

作者：

YANG, ZF ^{[1
]}

YU, SQ ^{[1
]}

CHEN, JY ^{[1
]}

机构：

[1] ACAD SINICA,INST CHEM MET,BEIJING 100080,PEOPLES R CHINA

来源：

JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY | 1994年 / 61卷 / 03期

关键词：

EXTRACTION; PENICILLIN-G; 1-HEXANOL; BUTYL ACETATE; DE-EMULSIFICATION;

D O I：

10.1002/jctb.280610311

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A solvent mixture of 1-hexanol and butyl acetate has been successfully used for the extraction of penicillin G. This solvent mixture may not only synergistically and effectively extract penicillin G, but also inhibit emulsion formation during the extraction of penicillin G from the filtrate of the fermentation broth. The equilibrium constants of the extraction, the molar ratios of 1-hexanol and penicillin G in the extracted species and the synergistic extraction of penicillin G have been studied by chemical analysis and by monitoring the absorbency shift in the FT-IR spectra of the functional groups in the solvents.

引用

页码：247 / 250

页数：4

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