FTSZ AND CELL-DIVISION

被引：24
|
作者：
BI, E
DAI, K
SUBBARAO, S
BEALL, B
LUTKENHAUS, J
机构：
[1] Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, KS USA, 66103, Kamsas City
来源：
RESEARCH IN MICROBIOLOGY | 1991年 / 142卷 / 2-3期
关键词：
FTSZ GENE; ESCHERICHIA-COLI; SEPTATION; BACILLUS-SUBTILIS;
D O I：
10.1016/0923-2508(91)90037-B
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The ftsZ gene in Escherichia coli is thought to be an essential gene and to play a pivotal role in cell division. Gene disruption experiments confirmed that ftsZ is an essential gene. Examination of cellular responses to FtsZ depletion indicated that FtsZ was required for division but not for nucleoid segregation. Analysis of mutations within the ftsZ, gene, selected for resistance to the cell division inhibitor SulA, revealed that they also conferred resistance to MinCD. This raises the possibility that ftsZ is the target of these two cell division inhibitors. Analysis of the ftsZ gene from Bacillus subtilis revealed that the gene was required for both septation during vegetative growth and asymmetric septation during sporulation.
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页码：249 / 252
页数：4
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