TOTAL SYNTHESES OF MAKALUVAMINE-A, MAKALUVAMINE-B, MAKALUVAMINE-C, MAKALUVAMINE-D AND MAKALUVAMINE-E, CYTOTOXIC PYRROLOIMINOQUINONE ALKALOIDS ISOLATED FROM MARINE SPONGE BEARING INHIBITORY ACTIVITIES AGAINST TOPOISOMERASE-II

被引：56

作者：

IZAWA, T ^{[1
]}

NISHIYAMA, S ^{[1
]}

YAMAMURA, S ^{[1
]}

机构：

[1] KEIO UNIV,FAC SCI & TECHNOL,DEPT CHEM,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON | 1994年 / 50卷 / 48期

关键词：

D O I：

10.1016/S0040-4020(01)85674-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Syntheses of makaluvamines A, B, C, D and E (1 - 5), new members of tetrahydropyrroloiminoquinone alkaloids, have been successfully carried out. Particularly, olefin introduction for makaluvamines B and E could be achieved by Pd - mediated and E(2) type methodologies.

引用

页码：13593 / 13600

页数：8