TRANSFORMING GROWTH-FACTOR-BETA - A NEW TYPE OF INHIBITOR OF PROLIFERATION OF NORMAL AND TUMOR-CELLS

被引：0
|
作者：
STOIKA, RS
KUSEN, SI
机构：
来源：
MOLECULAR BIOLOGY | 1990年 / 24卷 / 04期
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中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The activity of transforming growth factor-beta as an inhibitor of the proliferation of normal and tumor cells is reviewed, and the results of the authors' own studies are presented. Possible mechanisms of the modulation of this action by other growth factors and environmental conditions are considered. An attempt is made to define the role of transforming growth factor-beta in the overall system of regulation of cell proliferation at early stages of animal ontogenesis, and in carcinogenesis.
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页码：738 / 748
页数：11
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