AUTOCRINE GROWTH OF LEUKEMIC-CELLS

被引：9
|
作者：
JASMIN, C
GEORGOULIAS, V
SMADJAJOFFE, F
BOUCHEIX, C
LEBOUSSEKERDILES, C
ALLOUCHE, M
CIBERT, C
AZZARONE, B
机构：
[1] INSERM U 268, Hôpital Paul Brousse, 94800 Villejuif
来源：
LEUKEMIA RESEARCH | 1990年 / 14卷 / 08期
关键词：
Autocrine growth; autocrine loop; growth-factor; leukemia; paracrine growth; receptor;
D O I：
10.1016/0145-2126(90)90095-Q
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Autocrine growth is a process whereby a cell both secretes and responds to a growth factor. This paper describes the stepwise malignant progression of leukemic cells which has been demonstrated in many experimental models of autocrine leukemic growth. In contrast, autocrine growth has not been proven as a major physiopathological mechanism for the growth of leukemic cells in vivo in human myeloid and lymphocytic leukemias. Growth-factor independency of human leukemic cell lines may be due to clonal selection. © 1990.
引用
收藏
页码：689 / 693
页数：5
相关论文
共 50 条
  • [1] AUTOCRINE STIMULATION BY ERYTHROPOIETIN AND AUTONOMOUS GROWTH OF HUMAN ERYTHROID LEUKEMIC-CELLS INVITRO
    MITIAVILA, MT
    LECOUEDIC, JP
    CASADEVALL, N
    NAVARRO, S
    VILLEVAL, JL
    DUBART, A
    VAINCHENKER, W
    JOURNAL OF CLINICAL INVESTIGATION, 1991, 88 (03): : 789 - 797
  • [2] REGULATORS FOR GROWTH AND DIFFERENTIATION OF LEUKEMIC-CELLS
    OHTA, M
    ACTA HAEMATOLOGICA JAPONICA, 1990, 53 (08): : 1494 - 1501
  • [3] CLONAL GROWTH OF LEUKEMIC-CELLS INVITRO
    PREISLER, HD
    EPSTEIN, J
    CELL AND TISSUE KINETICS, 1981, 14 (04): : 395 - 404
  • [4] THE REGULATION OF GROWTH AND DEVELOPMENT OF NORMAL AND LEUKEMIC-CELLS
    DEXTER, TM
    ALLEN, TD
    JOURNAL OF PATHOLOGY, 1983, 141 (03): : 415 - 433
  • [5] AUTOCRINE GROWTH OF INTERLEUKIN 2-PRODUCING LEUKEMIC-CELLS IN A PATIENT WITH ADULT T-CELL LEUKEMIA
    ARIMA, N
    DAITOKU, Y
    OHGAKI, S
    FUKUMORI, J
    TANAKA, H
    YAMAMOTO, Y
    FUJIMOTO, K
    ONOUE, K
    BLOOD, 1986, 68 (03) : 779 - 782
  • [6] GROWTH AND RESPONSIVENESS OF HUMAN GRANULOCYTIC LEUKEMIC-CELLS INVITRO
    METCALF, D
    MOORE, MAS
    BIBLIOTHECA HAEMATOLOGICA, 1973, (40): : 235 - 241
  • [7] PHENOTYPE OF LEUKEMIC-CELLS
    KEMNITZ, J
    FREUND, M
    HELMKE, M
    CULLEN, P
    HUMAN PATHOLOGY, 1986, 17 (06) : 640 - 641
  • [8] INFLUENCE OF HEMATOPOIETIC GROWTH-FACTOR ON LEUKEMIC-CELLS
    RESNITZKY, P
    HARANGHERA, N
    EXPERIMENTAL HEMATOLOGY, 1994, 22 (01) : 1 - 1
  • [9] GROWTH-FACTOR REQUIREMENTS FOR NORMAL AND LEUKEMIC-CELLS
    MINDEN, M
    SEMINARS IN HEMATOLOGY, 1995, 32 (03) : 162 - 182
  • [10] INHIBITORY EFFECT OF BESTATIN ON THE GROWTH OF HUMAN LEUKEMIC-CELLS
    SAKURADA, K
    IMAMURA, M
    KOBAYASHI, M
    TACHIBANA, N
    ABE, K
    TANAKA, M
    OKABE, M
    MORIOKA, M
    KASAI, M
    SUGIURA, T
    MIYAZAKI, T
    ACTA ONCOLOGICA, 1990, 29 (06) : 799 - 802
12345