ANTIGENIC STUDY OF 337 STRAINS OF NEISSERIA-MENINGITIDIS ISOLATED IN MALI - EPIDEMIOLOGIC AND VACCINAL INTEREST

被引：4
|
作者：
KOUMARE, B
ACHTMAN, M
CISSE, M
WANG, JF
GIOVANNA, M
DOUMBIA, T
机构：
来源：
MEDECINE ET MALADIES INFECTIEUSES | 1995年 / 25卷 / 11期
关键词：
MENINGITIDIS; NEISSERIA MENINGITIDIS; VACCINES; OUTER MEMBRANE PROTEINS; MALI;
D O I：
10.1016/S0399-077X(05)80403-2
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Our work was about 337 strains of Neisseria meningitidis, isolated between 1989 and 1992 in Mali; 163 from CSF and 174 from throat. Serogroup C represents 90% of strains isolated from CSF et 33% of strains isolated from throat. Antigenic structure was determined. We found that serogroup A is P1.9 which is specific to clone IV.1 responsible for epidemic between 1981 and 1984 in Africa but actually endemic. Serogroup C has a new type of OMP1, unknown before, called by us P1-y. P1.y is typic to malian strains of serogroup C; it is rare or absent in strains from other countries (USA, Ghana, Burkina Faso, Italy).
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收藏
页码：1132 / 1136
页数：5
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