EFFECTS OF LONG-TERM TREATMENT WITH SERTRALINE (ZOLOFT(R)) SIMULATING HYPOTHYROIDISM IN AN ADOLESCENT

被引：9
|
作者：
HAREL, Z [1 ]
BIRO, FM [1 ]
TEDFORD, WL [1 ]
机构：
[1] CHILDRENS HOSP MED CTR,DEPT PEDIAT,DIV ADOLESCENT MED,CINCINNATI,OH 45229
来源：
JOURNAL OF ADOLESCENT HEALTH | 1995年 / 16卷 / 03期
关键词：
DEPRESSION; SERTRALINE (ZOLOFT); HYPOTHYROIDISM SIMULATION;
D O I：
10.1016/1054-139X(94)00069-Q
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
A 16-year-old depressed adolescent, who had received sertraline treatment for the previous 18 months, developed insomnia, daytime somnolence and lack of energy. His thyroid function tests revealed low levels of total T4 with normal levels of free T4 and TSH, and a normal thyrotropin-releasing hormone (TRH) stimulation test. Discontinuing sertraline resulted in improved sleep and disappearance of daytime somnolence. Although daytime somnolence and low levels of total T4 can mimic hypothyroidism, in this case sertraline only displaced the bound-fraction of total T4 and was not associated with true hypothyroidism.
引用
收藏
页码：232 / 234
页数：3
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