ORGANIZATION AND FUNCTION OF THE CYTOSKELETON IN POLARIZED EPITHELIAL-CELLS - A COMPONENT OF THE PROTEIN SORTING MACHINERY

被引：135
|
作者：
MAYS, RW
BECK, KA
NELSON, WJ
机构：
[1] Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford
来源：
CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 01期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0955-0674(94)90111-2
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Development and maintenance of cell-surface polarity in epithelial cells requires specialized localization of proteins to functionally and structurally distinct plasma membrane domains. The organization of these domains is dependent upon targeted delivery of transport vesicles between different membrane compartments, and upon protein sorting in the membranes of the Golgi complex and cell surface. Increasing evidence has been gathered in recent years that cytoskeletal components facilitate these processes.
引用
收藏
页码：16 / 24
页数：9
相关论文
共 50 条
  • [1] ROLE OF THE CYTOSKELETON AND PROTEIN SORTING IN THE SPATIAL-ORGANIZATION OF THE NA/K-ATPASE IN POLARIZED EPITHELIAL-CELLS
    NELSON, WJ
    HAMMERTON, RW
    WOLLNER, DA
    KRZEMINSKI, KA
    MAYS, R
    RYAN, T
    [J]. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 1991, 12 (05) : 488 - 488
  • [2] MECHANISMS OF PROTEIN SORTING AND TRAFFICKING IN POLARIZED EPITHELIAL-CELLS
    NELSON, WJ
    [J]. PEDIATRIC PULMONOLOGY, 1992, : 181 - 182
  • [3] PLASMA-MEMBRANE PROTEIN SORTING IN POLARIZED EPITHELIAL-CELLS
    MOSTOV, K
    APODACA, G
    AROETI, B
    OKAMOTO, C
    [J]. JOURNAL OF CELL BIOLOGY, 1992, 116 (03): : 577 - 583
  • [4] CYTOSKELETON ORGANIZATION IN CULTURED EPITHELIAL-CELLS
    SVITKINA, TM
    [J]. TSITOLOGIYA, 1989, 31 (12): : 1435 - &
  • [5] SORTING SIGNALS MAY NOT BE UNIVERSAL FOR POLARIZED PROTEIN SECRETION BY EPITHELIAL-CELLS
    ECAY, TW
    VALENTICH, JD
    [J]. JOURNAL OF GENERAL PHYSIOLOGY, 1988, 92 (06): : A18 - A19
  • [6] MEMBRANE FLUIDITY IN THE ORGANIZATION OF CYTOSKELETON IN EPITHELIAL-CELLS
    SAUK, JJ
    KRUMWEIDE, M
    JOHNSON, D
    WHITE, JG
    [J]. JOURNAL OF DENTAL RESEARCH, 1986, 65 : 177 - 177
  • [7] RAB5A IS A COMMON COMPONENT OF THE APICAL AND BASOLATERAL ENDOCYTIC MACHINERY IN POLARIZED EPITHELIAL-CELLS
    BUCCI, C
    WANDINGERNESS, A
    LUTCKE, A
    CHIARIELLO, M
    BRUNI, CB
    ZERIAL, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (11) : 5061 - 5065
  • [8] GLYCOPHOSPHOLIPID MEMBRANE ANCHORING PROVIDES CLUES TO THE MECHANISM OF PROTEIN SORTING IN POLARIZED EPITHELIAL-CELLS
    LISANTI, MP
    RODRIGUEZBOULAN, E
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 1990, 15 (03) : 113 - 118
  • [9] SORTING AND ENDOCYTOSIS OF VIRAL GLYCOPROTEINS IN TRANSFECTED POLARIZED EPITHELIAL-CELLS
    GOTTLIEB, TA
    GONZALEZ, A
    RIZZOLO, L
    RINDLER, MJ
    ADESNIK, M
    SABATINI, DD
    [J]. JOURNAL OF CELL BIOLOGY, 1986, 102 (04): : 1242 - 1255
  • [10] THE POLARIZED ORGANIZATION OF THE ENDOCYTIC PATHWAYS IN MDCK EPITHELIAL-CELLS
    PARTON, RG
    BOMSEL, M
    GRIFFITHS, G
    GRUENBERG, J
    SIMONS, K
    [J]. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1991, 39 (05) : 717 - 717
12345