CYTOGENETIC STUDIES IN 5 PATIENTS WITH SEZARY-SYNDROME

被引：13
|
作者：
SOLE, F
WOESSNER, S
VALLESPI, T
LOSADA, AP
FLORENSA, L
IRRIGUIBLE, D
VILA, J
SANSSABRAFEN, J
机构：
[1] UNIV BARCELONA,HOSP GEN VALLE HEBRON,SERV HEMATOL & HEMOTERAPIA,BARCELONA,SPAIN
[2] HOSP SAGRAT COR,UNITAT HEMATOL,BARCELONA,SPAIN
来源：
CANCER GENETICS AND CYTOGENETICS | 1994年 / 75卷 / 02期
关键词：
D O I：
10.1016/0165-4608(94)90164-3
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A cytogenetic study was performed in five patients with Sezary syndrome. Metaphases were obtained from a phytohemaggluyinin-stimulated lymphocyte culture. The five patients showed abnormal karyotypes. The chromosomes preferentially involved in numerical aberrations were chromosomes 10 (monosomy) and 13 (monosomy); involved in structural changes were chromosomes 1, 2, 4, 6, and 14. In our series, all patients showed progression of the disease.
引用
收藏
页码：130 / 132
页数：3
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