SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 28-HOMOBRASSINOLIDE AND ANALOGS

被引：35
|
作者：
MCMORRIS, TC
PATIL, PA
CHAVEZ, RG
BAKER, ME
CLOUSE, SD
机构：
[1] UNIV CALIF SAN DIEGO,DEPT MED,LA JOLLA,CA 92093
[2] SAN DIEGO STATE UNIV,DEPT BIOL,SAN DIEGO,CA 92182
来源：
PHYTOCHEMISTRY | 1994年 / 36卷 / 03期
关键词：
BRASSINOSTEROIDS; 28-HOMOBRASSINOLIDE; STIGMASTEROL; SOYBEAN EPICOTYL ELONGATION; SIDE CHAIN CONFORMATION;
D O I：
10.1016/S0031-9422(00)89779-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
28-Homobrassinolide has been synthesized from stigmasterol in an overall yield of 21%. The biological activity of 28-homobrassinolide, brassinolide, 24-epiibrassinoide, 22S,23S,24-epibrassinolide, and 22S,23S,28-homobrassinolides have been compared in the soybean epicotyl elongation assay. All the steroids except 22S,23S,28-homobrassinolide exhibited a similar biological activity, but the latter compound was substantially less active. There appears to be a correlation between biological activity and overall dimensions of the steroidal side chain.
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收藏
页码：585 / 589
页数：5
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