VITAMIN D DEFICIENCY IN PATIENTS WITH THYROID DISORDER

OBJECTIVE: To determine the vitamin D deficiency in patients with thyroid disorder. STUDY DESIGN AND SETTING: This was a cross-sectional study and carried out ant medicine department of Indus medical college Tando Muhammad khan. Study duration was 6 month from December 2016 July 2017. MATERIAL AND METHODS: All the thyroid disorder patients, either gender were studied. All the patients with thyroid carcinoma, diabetes, lactation and known cases of chronic hepatitis excluded from study. 5ml blood was taken from each patient for assessment of vitamin D level. All the data regarding age, gender, hypothyroidism and hyperthyroidism was entered in proforma. RESULTS: Total 67 patients of thyroid disorder were selected, their mean age was 39.75 +/- 5.61 years. Female gender was most common as 62.7%. A positive correlation was found between vitamin D level and TSH r-value = 0.015. Total 43.3% thyroid disorder patients were found with vitamin D deficiency, insufficiency was 33.3% and 25.4% patients were with normal vitamin D level. No significant association was found in vitamin D efficiency according to hypothyroidism and hyperthyroidism p-value 0.992. CONCLUSION: It is concluded that vitamin D deficiency was 43.3% and insufficiency was 31.3% and positive correlation was found between vitamin D level and TSH. The pleiotropic roles of vitamin D have been recognized through preclinical and observational studies which have suggested a beneficial role of vitamin D in the management of thyroid disease.