PREFORMULATION STUDIES ON NAPROXEN SODIUM SUPPOSITORIES

被引：0
|
作者：
SANTUS, G [1 ]
GIORDANO, F [1 ]
GAZZANIGA, A [1 ]
BRUNI, G [1 ]
PAIOTTI, S [1 ]
YAN, JX [1 ]
机构：
[1] UNIV PAVIA,DEPT PHARMACEUT CHEM,VIALE TARAMELLI 12,I-27100 PAVIA,ITALY
来源：
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS | 1994年 / 40卷 / 04期
关键词：
NAPROXEN SODIUM; CALCIUM LEVULINATE; SUPPOSITORIES; PREFORMULATION; THERMAL ANALYSIS; CHEMICAL STABILITY; TECHNOLOGICAL STABILITY;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The results of compatibility studies on a formulation for suppositories containing naproxen sodium, calcium levulinate and a tat base (Monoleno OH-6) are reported. Thermal analysis (DSC) was mainly used for preformulation studies on the components, their mixtures and their reaction products. Naproxen sodium and calcium levulinate were found to interact, depending on experimental conditions, deeply modifying the technological properties of suppositories.
引用
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页码：243 / 245
页数：3
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