TRISOMY-5 IN LONG-TERM CULTURES FROM BONE-MARROW OF PATIENTS WITH SOLID TUMORS

被引：6

作者：

OZISIK, YY ^{[1
]}

MORGAN, R ^{[1
]}

PEIER, A ^{[1
]}

MELONI, AM ^{[1
]}

SANDBERG, AA ^{[1
]}

机构：

[1] SW BIOMED RES INST & GENETRIX INC,CTR CANC,SCOTTSDALE,AZ 85251

来源：

CANCER GENETICS AND CYTOGENETICS | 1994年 / 78卷 / 02期

关键词：

D O I：

10.1016/0165-4608(94)90091-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Long-term cultures of bone marrow from 15 cases diagnosed previously with primary solid tumors were analyzed cytogenetically. Of these cases, 10 had normal karyotypes and five had chromosomal abnormalities. Trisomy 5 was found in four cases, three with trisomy 5 as the only change and one with trisomy 5 and trisomy 12. These results suggest that trisomy 5 may be a nonrandom change associated with an in vitro or in vivo phenomenon.

引用

页码：207 / 209

页数：3

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