A Review of Management of Clostridium difficile Infection: Primary and Recurrence

被引：8
|
作者：
Vincent, Yasmeen [1 ]
Manji, Arif [1 ]
Gregory-Miller, Kathleen [1 ]
Lee, Christine [1 ,2 ]
机构：
[1] St Josephs Healthcare Hamilton, Hamilton, ON L8N 4A6, Canada
[2] McMaster Univ, Dept Pathol & Mol Med, Hamilton Reg Lab, Program Med, Hamilton, ON L8S 4L8, Canada
来源：
ANTIBIOTICS-BASEL | 2015年 / 4卷 / 04期
关键词：
recurrence; Clostridium difficile infection; fecal microbiota transplantation (FMT); probiotics; immunotherapy; antibiotics;
D O I：
10.3390/antibiotics4040411
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Clostridium difficile infection (CDI) is a potentially fatal illness, especially in the elderly and hospitalized individuals. The recurrence and rates of CDI are increasing. In addition, some cases of CDI are refractory to the currently available antibiotics. The search for improved modalities for the management of primary and recurrent CDI is underway. This review discusses the current antibiotics, fecal microbiota transplantation (FMT) and other options such as immunotherapy and administration of non-toxigenic Clostridium difficile (CD) for the management of both primary and recurrent CDI.
引用
收藏
页码：411 / 423
页数：13
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