Metabolic syndrome in the indigenous population of Yakutia

被引：0
|
作者：
Osakovskij, V. L. [1 ]
Goldfarb, L. G. [4 ,5 ]
Klimova, T. M. [2 ]
Sambuugin, N. [6 ]
Odgerel, Z. [7 ]
Yakovleva, M. N. [1 ]
Ignatiev, P. M. [8 ]
Alexeeva, L. L. [9 ]
Baltakhinova, M. E. [3 ]
Timofeev, G. A. [1 ]
Krivoshapkin, V. G. [1 ,4 ]
Platonov, F. A. [1 ,4 ]
机构：
[1] NINDS, Inst Neurol, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA
[2] NINDS, GCC Monitoring & Prevent Grp, Inst Neurol, NIH, Bethesda, MD 20892 USA
[3] NINDS, Funct Res Cabinet, Inst Neurol, NIH, Bethesda, MD 20892 USA
[4] NINDS, Med Sci, Inst Neurol, NIH, Bethesda, MD 20892 USA
[5] NINDS, Dept Neurogenet, Inst Neurol, NIH, Bethesda, MD 20892 USA
[6] Uniformed Serv Univ Hlth Sci, Dept Anesthesiol, Med Sci, Bethesda, MD 20814 USA
[7] NIH, Dept Clin Neurogenet, Inst Neurol, Bethesda, MD 20892 USA
[8] Yakut Republican Endocrinol Dispensary Minist Pub, State Inst, Yakutia, Russia
[9] Yakut Basic Med Coll, Yakutsk, Russia
来源：
YAKUT MEDICAL JOURNAL | 2010年 / 02期
关键词：
a metabolic syndrome; frequency; abdominal adiposity; diabetes; insulin resistance; genes of predisposition; cytokines; a fatty tissue; endothelium;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
In the article prevalence and clinical variants of a metabolic syndrome among the native population of Yakutia are considered. On an example of type 2 diabetes in representatives of the Yakut population a role of a metabolic syndrome and system inflammatory process in development of a somatic pathology is discussed. Results of genetic researches of polymorphic variants of genes (LPL, IL6, RSTN, ABCC8), causing predisposition of the Yakut population representatives to development of metabolic disturbances, insulin resistance and to disease by type 2 diabetes are presented.
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收藏
页码：98 / 102
页数：5
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