PRODUCTION OF GLUCONIC ACID BY ASPERGILLUS-NIGER IMMOBILIZED ON POLYURETHANE FOAM

被引：0
|
作者：
VASSILEV, NB [1 ]
VASSILEVA, MC [1 ]
SPASSOVA, DI [1 ]
机构：
[1] BULGARIAN ACAD SCI,INST MICROBIOL,BU-1113 SOFIA,BULGARIA
来源：
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 1993年 / 39卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Production of gluconic acid by cells of Aspergillus niger immobilized on polyurethane foam was studied in repeated-batch shake-flask and bubble-column fermentations. For passive immobilization, various amounts of polyurethane foam and spore suspension were tested in order to obtain a suitable combination for optimal concentration of immobilized biomass. Immobilized cells were sucessfully reused with higher levels of product formation being maintained for longer period (65-70 h) than free cells. The highest gluconic acid concentration of about 143 g l-1 was reached on hydrol-based production medium with 0.3-cm3 foam cubes in the bubble column, where the effect of more suitable aeration and particle volume: medium volume ratio scheme was also investigated.
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页码：285 / 288
页数：4
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