IN-VITRO EFFECTS OF MYCOPLASMA-PULMONIS ON MURINE NATURAL-KILLER-CELL ACTIVITY

被引：0
|
作者：
SWING, SP
DAVIS, JK
EGAN, ML
机构：
[1] UNIV ALABAMA,SCH MED,DEPT COMPARAT MED,BIRMINGHAM,AL 35294
[2] UNIV ALABAMA,SCH MED,DEPT MICROBIOL,BIRMINGHAM,AL 35294
[3] UNIV ALABAMA,SCH DENT,DEPT COMPARAT MED,BIRMINGHAM,AL 35294
[4] UNIV ALABAMA,SCH DENT,DEPT MICROBIOL,BIRMINGHAM,AL 35294
来源：
LABORATORY ANIMAL SCIENCE | 1995年 / 45卷 / 04期
关键词：
D O I：
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中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
We evaluated the effect of coculture of virulent and avirulent strains of Mycoplasma pulmonis with mononuclear cells from resistant and susceptible strains of mice on natural killer (NK) cell activity against YAC-1 cells in a standard 4-h Cr-51-release assay. Endogenous NK activity was minimal in the specific-pathogen-free-mice without an external stimulus. There was no correlation between in vivo virulence of the mycoplasmas or host resistance and the in vitro stimulation of NK cell activity. Only two of the avirulent strains of M. pulmonis tested induced signifcant increases in NK cell activity, and virulent M. pulmonis increased activity only in cells from susceptible C3H/HeN
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页码：352 / 356
页数：5
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