ONE-DIMENSIONAL STEADY INVISCID FLOW THROUGH A STENOTIC COLLAPSIBLE TUBE

被引:26
|
作者
KU, DN
ZEIGLER, MN
DOWNING, JM
机构
[1] George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA
关键词
D O I
10.1115/1.2891209
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A one-dimensional inviscid solution for flow through a compliant tube with a stenosis is presented. The model is used to represent an artery with an atherosclerotic plaque and to investigate a range of conditions for which arterial collapse may occur. The coupled equations for flow through collapsible tubes are solved using a Runge-Kutta finite difference scheme. Quantitative results are given for specific physiological parameters including inlet and outlet pressure, flow rate, stenosis size, length and stiffness. The results suggest that high-grade stenotic arteries may exhibit collapse with typical physiological pressures. Critical stenoses may cause choking of flow at the throat followed by a transition to supercritical flow with tube collapse downstream. Greater amounts of stenosis produced a linear reduction of flow rate and a shortening of the collapsed region. Changes in stenosis length created proportional changes in the length of collapse. Increasing the stiffness of the stenosis to a value greater than the nominal tube stiffness caused a greater amount of flow limitation and more negative pressures, compared to a stenosis with constant stiffness. These findings assist in understanding the clinical consequences of flow through atherosclerotic arteries. © 1990 by ASME.
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页码:444 / 450
页数:7
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