Fields in a concentrated area of soybean production in South Carolina were chosen for soil sampling to determine the distribution of plant-parasitic nematodes. Five hundred sampling sites were distributed over 19 counties according to county soybean acreage. Helicotylenchus and Scutellonema were identified most frequently from soil samples; together, these genera occurred in over 70% of the samples. Pratylenchus and Paratrichodorus were each observed in more than 60% of fields. Meloidogyne spp. were found in 27% of the fields and Hoplolaimus columbus in 14%. Rotylenchulus reniformis and Belonolaimus sp. each occurred in less than 10% of the fields. Tylenchorhynchus and Mesocriconema (Criconemella) were each present in over 40% of the fields, but numbers from each field were low. Of the fields sampled, 14% contained Heterodera glycines. Of these, 47% were race 14 and 32% were race 3. Races 9, 6, and 10 were also observed.