PREPARATION AND TRANSFUSION OF POSITIVELY SELECTED CD34-POSITIVE PERIPHERAL-BLOOD STEM-CELLS

被引：0

作者：

HOCKER, P

FRIEDL, J

KURZ, M

DOSSENBACHGLANINGER, A

KAHLS, P

GREINIX, H

KUHRER, I

GERHARTL, K

WAGNER, A

机构：

[1] AKH WIEN,HAMATOL & HAMOSTASEOL ABT,VIENNA,AUSTRIA

[2] WILHELMINENSPITAL STADT WIEN,MED ABT 1,VIENNA,AUSTRIA

来源：

INFUSIONSTHERAPIE UND TRANSFUSIONSMEDIZIN | 1995年 / 22卷

关键词：

PERIPHERAL BLOOD STEM CELLS; IMMUNADSORPTION; STEM CELL APHERESIS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Great amounts of haematopoietic stem cells can be collected after conditioning with growth factors and myelosuppressive treatment. With the immunadsorption technique (Ceprate SC(R)) CD34+ cells can be purified and concentrated with an overall loss of about 20-40%. Retransfusion of CD34+ purified cells resulted in a rapid and sustained engraftment after myeloablative treatment. Thus CD34+ selection by immunadsorption offers the opportunity to purify stem cells concentrates from platelets, red cells and granulocytes and to minimize DMSO toxicity.

引用

页码：123 / 124

页数：2

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