POMC GENE-EXPRESSION IN MOUSE AND HAMSTER MELANOMA-CELLS

被引：48
|
作者：
SLOMINSKI, A
机构：
[1] Department of Immunology and Microbiology, Albany Medical College, Albany
来源：
FEBS LETTERS | 1991年 / 291卷 / 02期
关键词：
PROOPIOMELANOCORTIN; BETA-ENDORPHIN; MELANOMA;
D O I：
10.1016/0014-5793(91)81274-C
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Expression of mRNA hybridizable to murine POMC cDNA, and immunoreactivity specific for POMC derived peptide, beta-endorphin, are reported for the first time in one murine and two hamster melanoma lines. The apparent sizes of POMC mRNA transcript were 3.5, 1.5 and 1 kb. It is suggested that POMC gene expression may be involved in the autoregulation of the melanoma phenotype at the cellular and tissue levels.
引用
收藏
页码：165 / 168
页数：4
相关论文
共 50 条
12345