EFFECT OF VASCULAR PUNCTURE ON BLOOD-GASES IN THE NEWBORN

Continuous monitoring methods have shown changes of oxygenation in neonates during various procedures. However, actual changes in blood gases during vascular punctures have not been reported. We studied the effect of vascular puncture on arterial blood gases during routine venipuncture in 17 neonates who had indwelling arterial catheters. Arterial blood gases were analyzed before, during, and following recovery from venipuncture. Ventilator settings were not changed during the study, though oxygen concentration (Fi(O2)) was adjusted as indicated by continuous P(O2) or saturation monitors. During venipuncture, there was a significant fall in Pa(CO2) from 38 +/- 5 to 32 +/- 7 mmHg (P < 0.0001) and in Pa(CO2) from 75 +/- 21 to 58 +/- 23 mmHg (P < 0.0001). Following venipuncture, both values returned to baseline. The results of this study imply that blood gases obtained by intermittent arterial sticks may provide data that do not accurately reflect the neonates' respiratory status.