MICROENCAPSULATION OF PROPRANOLOL HYDROCHLORIDE BY THE SOLVENT EVAPORATION TECHNIQUE

被引：8
|
作者：
MANEKAR, NC
PURANIK, PK
JOSHI, SB
机构：
[1] Department of Pharmaceutical Sciences, Nagpur University, Nagpur, (MS)
来源：
JOURNAL OF MICROENCAPSULATION | 1992年 / 9卷 / 01期
关键词：
D O I：
10.3109/02652049209021223
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Propranolol hydrochloride microcapsules were prepared by the coacervation-phase separation induced by solvent evaporation technique. The cellulose acetate phthalate was employed as coating material alone and in combination with ethyl cellulose. The prepared microcapsules were evaluated for their drug content, particle size distribution (microscopic method), flow properties, bulk density, in vitro dissolution and drug release kinetics.
引用
收藏
页码：63 / 66
页数：4
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