EFFECTS OF DIETARY-CHOLESTEROL AND PHYTOSTEROL OVERLOAD ON WISTAR RAT PLASMA-LIPIDS

被引：19

作者：

LARAKI, L ^{[1
]}

PELLETIER, X ^{[1
]}

DEBRY, G ^{[1
]}

机构：

[1] UNIV NANCY 1,CTR NUTR HUMAINE,DEPT NUTR & MALADIES METAB,40 RUE LIONNOIS,F-54000 NANCY,FRANCE

来源：

ANNALS OF NUTRITION AND METABOLISM | 1991年 / 35卷 / 04期

关键词：

DIET; PHYTOSTEROLS; CHOLESTEROL; LIPOPROTEINS; TRIGLYCERIDES; PLASMA; RAT;

D O I：

10.1159/000177649

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To study the effects of dietary phytosterols on plasma cholesterol, Wistar rats were fed diets containing a cholesterol overload (24 mg/day), to which phytosterols were added or not (24 or 96 mg/day). The cholesterol overload led to a marked increase in cholesterol, mainly linked to very-low-density and low-density lipoproteins. Phytosterols reduced those effects, the highest dose being most efficient. No undesirable effect was observed either on body or on liver weights. This shows that low doses of phytosterols are sufficient to significantly decrease a plasma cholesterol enhancement induced by a dietary cholesterol overload.

引用

页码：221 / 225

页数：5

共 50 条

[1] HYPERCHOLESTEROLEMIC EFFECT OF DIETARY-CHOLESTEROL IN DIETS ENRICHED IN POLYUNSATURATED AND SATURATED FAT - DIETARY-CHOLESTEROL, FAT-SATURATION, AND PLASMA-LIPIDS
LICHTENSTEIN, AH
AUSMAN, LM
CARRASCO, W
JENNER, JL
ORDOVAS, JM
SCHAEFER, EJ
[J]. ARTERIOSCLEROSIS AND THROMBOSIS, 1994, 14 (01): : 168 - 175
[2] DIETARY-CHOLESTEROL AND THE PLASMA-LIPIDS AND LIPOPROTEINS IN THE TARAHUMARA INDIANS - A PEOPLE HABITUATED TO A LOW CHOLESTEROL DIET AFTER WEANING
MCMURRY, MP
CONNOR, WE
CERQUEIRA, MT
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1982, 35 (04): : 741 - 744
[3] EFFECTS OF DIETARY-CHOLESTEROL AND FASTING ON HAMSTER PLASMA-LIPOPROTEIN LIPIDS
WEINGAND, KW
DAGGY, BP
[J]. EUROPEAN JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY, 1991, 29 (07): : 425 - 428
[4] EFFECT OF SUCROSE POLYESTER ON PLASMA-LIPIDS AND CHOLESTEROL ABSORPTION IN AFRICAN-GREEN MONKEYS WITH VARIABLE HYPERCHOLESTEROLEMIC RESPONSE TO DIETARY-CHOLESTEROL
STCLAIR, RW
WOOD, LL
CLARKSON, TB
[J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 1981, 30 (02): : 176 - 183
[5] EFFECTS OF THE NATURE OF DIETARY PROTEINS, LECITHIN AND METHIONINE ON RAT PLASMA-LIPIDS
CHANDRASIRI, V
VILLAUME, C
BAU, HM
MEJEAN, L
[J]. ARCHIVES INTERNATIONALES DE PHYSIOLOGIE DE BIOCHIMIE ET DE BIOPHYSIQUE, 1991, 99 (04): : 291 - 295
[6] EFFECTS OF INCREASING DIETARY-CHOLESTEROL, AS PART OF AN AHA STEP-1 DIET, ON PLASMA-LIPIDS AND LIPOPROTEINS IN HEALTHY-YOUNG MEN
GINSBERG, HN
KARMALLY, W
SIDDIQUI, M
HOLLERAN, S
RAMAKRISHNAN, R
[J]. CLINICAL RESEARCH, 1993, 41 (02): : A390 - A390
[7] EFFECTS OF INCREASING DIETARY-CHOLESTEROL, AS PART OF AN AHA STEP-1 DIET, ON PLASMA-LIPIDS AND LIPOPROTEINS IN HEALTHY-YOUNG MEN
KARMALLY, W
SIDDIQUI, M
NGAI, C
TALL, AR
HOLLERAN, S
RAMAKRISHNAN, R
GINSBERG, HN
[J]. CIRCULATION, 1993, 88 (04) : 318 - 318
[8] EFFECT OF DIETARY-CHOLESTEROL AND SATURATED FATS ON PLASMA-LIPIDS, LIPOPROTEINS AND APOPROTEINS ON HUMAN-SUBJECTS FED NATURAL DIETS
ZANNI, EE
ZANNIS, VI
BRESLOW, JL
BLUM, C
[J]. ARTERIOSCLEROSIS, 1984, 4 (05): : A561 - A561
[9] UCLA DIET STUDY .3. LACK OF CORRELATION BETWEEN DIETARY-CHOLESTEROL AND PLASMA-LIPIDS IN 429-MEN
SLATER, GG
ALFINSLATER, RB
[J]. FEDERATION PROCEEDINGS, 1982, 41 (03) : 719 - 719
[10] EXCESSIVE FAT AND CHOLESTEROL INTAKE IN HYPERCHOLESTEROLEMIC SUBJECTS - EFFECTS OF DIETARY INTERVENTION ON PLASMA-LIPIDS AND LIPOPROTEIN CHOLESTEROL
ROS, E
ZAMBON, D
CUSO, E
[J]. MEDICINA CLINICA, 1989, 92 (02): : 41 - 46

← 1 2 3 4 5 →