HEPATOMA MERBARONE - A SOUTHWEST-ONCOLOGY-GROUP STUDY

被引：1
|
作者：
POPLIN, EA
TANGEN, CM
HARVEY, WH
MACDONALD, JS
机构：
[1] WAYNE STATE UNIV,MED CTR,DETROIT,MI 48202
[2] SW ONCOL GRP,CTR STAT,SEATTLE,WA
[3] HEMATOL ONCOL ASSOCIATES SW FLORIDA,NAPLES,FL
[4] TEMPLE UNIV,PHILADELPHIA,PA 19122
来源：
INVESTIGATIONAL NEW DRUGS | 1994年 / 12卷 / 04期
关键词：
HEPATOMA; MERBARONE; HEPATOCELLULAR CARCINOMA; TOXICITY;
D O I：
10.1007/BF00873051
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Sixteen eligible patients with hepatocellular carcinoma, previously untreated, received merbarone 1000 mg/m(2)/d for five consecutive days every 21 days. No complete or partial response to treatment was obtained. Seven patients had grade 4 granulocytopenia. One patient died with renal failure. Merbarone in this dose and schedule was ineffective in the treatment of hepatocellular carcinoma.
引用
收藏
页码：337 / 340
页数：4
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