Over time, the comparative analysis of capitalism has moved beyond the strict confines of the narrow varieties of capitalism (VoC) framework. In this sense, it is possible to observe an emergent post-VoC discussion that goes beyond the static design and methodological nationalism that can be found in a strictly comparative and institutionalist account of capitalism. So far, however, the post-VoC discussion has been barely able to address important politico-economic and societal themes and issues. For the most part, assertions about time-diagnostic characterisations of the current state of capitalism, the causes and processes of specific crisis dynamics inherent to this current form of capitalism, and the asymmetrical forms of international networks or formative transnational power relations, remain weak or chaotic. In order to overcome these existing deficiencies, this paper argues from an analytical perspective that situates itself in regulation theory and allows itself to be characterised as an extended neo-Gramscian international political economy (IPE) approach.