THE PORCINE INTESTINAL RECEPTOR FOR ESCHERICHIA-COLI K88-ALPHA-B, K88-ALPHA-C - REGIONAL LOCALIZATION ON CHROMOSOME-13 AND INFLUENCE OF IGG RESPONSE TO THE K88 ANTIGEN

被引：72
|
作者：
EDFORSLILJA, I [1 ]
GUSTAFSSON, U [1 ]
DUVALIFLAH, Y [1 ]
ELLERGREN, H [1 ]
JOHANSSON, M [1 ]
JUNEJA, RK [1 ]
MARKLUND, L [1 ]
ANDERSSON, L [1 ]
机构：
[1] INRA,CTR RECH JOUY EN JOSAS,ECOL & PHYSIOL SYST DIGEST LAB,F-78352 JOUY EN JOSAS,FRANCE
来源：
ANIMAL GENETICS | 1995年 / 26卷 / 04期
关键词：
ANTIBODY RESPONSE; CHROMOSOME; 13; ESCHERICHIA COLI; K88; RECEPTOR; LINKAGE; PIG;
D O I：
10.1111/j.1365-2052.1995.tb03250.x
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
The loci encoding the porcine intestinal receptors for Escherichia call K88ab and K88ac (K88abR and K88acR) were firmly assigned to chromosome 13 by linkage analysis using a three-generation pedigree. The linear order of these loci and seven other markers on chromosome 13 was determined by multipoint analyses, The K88abR and K88acR loci were tightly linked (theta ($) over cap = 0.01, Z ($) over cap = 41.06) with the K88abR locus localized 7.4 cM (sex average) proximal to the transferrin locus. The results, together with previous reports from two other groups, provide an unequivocal assignment of the K88 receptor loci to chromosome 13, and reject a previous assignment to chromosome 4. Pigs possessing the receptor had a slightly higher specific IgG response to the K88 antigen after an intramuscular immunization with an E. coli vaccine.
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页码：237 / 242
页数：6
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