ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ACTIVITIES OF U-90152 AND U-75875 IN HUMAN BRAIN-CELL CULTURES

被引：4

作者：

PETERSON, PK

GEKKER, G

HU, SX

CHAO, CC

机构：

[1] MINNEAPOLIS MED RES FDN INC,NEUROIMMUNOBIOL & HOST DEF LAB,MINNEAPOLIS,MN

[2] UNIV MINNESOTA,SCH MED,MINNEAPOLIS,MN 55455

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 10期

关键词：

D O I：

10.1128/AAC.38.10.2465

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Antiviral activities of the reverse transcriptase inhibitors U-90152 and 3'-azido-2',3'-dideoxythymidine and the protease inhibitor U-75875 were compared in two culture models of human immunodeficiency virus type 1 brain infection. In a model involving acutely infected microglial cells, U-90152 was the most active, whereas in a model using chronically infected promonocytes, U-75875 was the most active.

引用

页码：2465 / 2468

页数：4

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