Exposure to flame retardants in European children - Results from the HBM4EU aligned studies

被引：0

作者：

van der Schyff, Veronica ^{[1
]}

Kalina, Jiri ^{[1
]}

Govarts, Eva ^{[2
]}

Gilles, Liese ^{[2
]}

Schoeters, Greet ^{[2
,3
]}

Castano, Argelia ^{[4
]}

Esteban-Lopez, Marta ^{[4
]}

Kohoutek, Jiri ^{[1
]}

Kukucka, Petr ^{[1
]}

Covaci, Adrian ^{[5
]}

Koppen, Gudrun ^{[2
]}

Andryskova, Lenka ^{[1
]}

Piler, Pavel ^{[1
]}

Klanova, Jana ^{[1
]}

Jensen, Tina Kold ^{[6
]}

Rambaud, Loic ^{[7
]}

Riou, Margaux ^{[7
]}

Lamoree, Marja ^{[8
]}

Kolossa-Gehring, Marike ^{[9
]}

Vogel, Nina ^{[9
]}

Weber, Till ^{[9
]}

Goeen, Thomas ^{[10
]}

Gabriel, Catherine ^{[11
,12
]}

Sarigiannis, Dimosthenis A. ^{[11
,12
,13
]}

Sakhi, Amrit Kaur ^{[14
]}

Haug, Line Smastuen ^{[14
]}

Murinova, Lubica Palkovicova ^{[15
]}

Fabelova, Lucia ^{[15
]}

Tratnik, Janja Snoj ^{[16
]}

Mazej, Darja ^{[16
]}

Melymuk, Lisa ^{[1
]}

机构：

[1] Masaryk Univ, Fac Sci, RECETOX, Kotlarska 2, Brno, Czech Republic

[2] Flemish Inst Technol Res VITO, VITO Hlth, B-2400 Mol, Belgium

[3] Univ Antwerp, Dept Biomed Sci, B-2020 Antwerp, Belgium

[4] Inst Salud Carlos III, Natl Ctr Environm Hlth, Madrid, Spain

[5] Univ Antwerp, Toxicol Ctr, B-2610 Antwerp, Belgium

[6] Univ Southern Denmark, Inst Publ Hlth, Dept Environm Med, DK-5000 Odense, Denmark

[7] French Publ Hlth Agcy ANSP, Sante Publ France, F-94415 St Maurice, France

[8] Vrije Univ, Amsterdam Inst Life & Environm, Sect Chem Environm & Hlth, Boelelaan 1108, NL-1081 HZ Amsterdam, Netherlands

[9] German Environm Agcy UBA, D-06844 Dessau Rosslau, Germany

[10] IPASUM Inst & Outpatient Clin Occupat Social & Env, Henkestr 9-11, D-91054 Erlangen, Germany

[11] Aristotle Univ Thessaloniki, Dept Chem Engn, Environm Engn Lab, Thessaloniki 54124, Greece

[12] HERACLES Res Ctr Exposome & Hlth, Ctr Interdisciplinary Res & Innovat, Balkan Ctr, Bldg B,10th km Thessaloniki Thermi Rd, Thessaloniki 57001, Greece

[13] Inst Adv Study, Environm Hlth Engn, Piazza Vittoria 15, I-27100 Pavia, Italy

[14] Norwegian Inst Publ Hlth, Dept Environm Hlth, Oslo, Norway

[15] Slovak Med Univ, Fac Publ Hlth, Bratislava 83303, Slovakia

[16] Jozef Stefan Inst, Dept Environm Sci, Ljubljana 1000, Slovenia

来源：

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH | 2023年 / 247卷

关键词：

Polybrominated diphenyl ethers; Organophosphate flame retardants; Children; Europe; HBM4EU; Human biomonitoring;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Many legacy and emerging flame retardants (FRs) have adverse human and environmental health effects. This study reports legacy and emerging FRs in children from nine European countries from the HBM4EU aligned studies. Studies from Belgium, Czech Republic, Germany, Denmark, France, Greece, Slovenia, Slovakia, and Norway conducted between 2014 and 2021 provided data on FRs in blood and urine from 2136 children. All samples were collected and analyzed in alignment with the HBM4EU protocols. Ten halogenated FRs were quantified in blood, and four organophosphate flame retardants (OPFR) metabolites quantified in urine. Hex-abromocyclododecane (HBCDD) and decabromodiphenyl ethane (DBDPE) were infrequently detected (<16% of samples). BDE-47 was quantified in blood from Greece, France, and Norway, with France (0.36 ng/g lipid) having the highest concentrations. BDE-153 and-209 were detected in <40% of samples. Dechlorane Plus (DP) was quantified in blood from four countries, with notably high median concentrations of 16 ng/g lipid in Slovenian children. OPFR metabolites had a higher detection frequency than other halogenated FRs. Diphenyl phosphate (DPHP) was quantified in 99% of samples across 8 countries at levels similar to 5 times higher than other OPFR metabolites (highest median in Slovenia of 2.43 ng/g lipid). FR concentrations were associated with lifestyle factors such as cleaning frequency, employment status of the father of the household, and renovation status of the house, among others. The concentrations of BDE-47 in children from this study were similar to or lower than FRs found in adult matrices in previous studies, suggesting lower recent exposure and effectiveness of PBDE restrictions.

引用

页数：10

共 50 条

[1] Exposure to flame retardants in European children - Results from the HBM4EU aligned studies
van Der Schyff, Veronica
Kalina, Jiri
Govarts, Eva
Gilles, Liese
Schoeters, Greet
Castano, Argelia
Esteban-Lopez, Marta
Kohoutek, Jiri
Kukucka, Petr
Covaci, Adrian
Koppen, Gudrun
Andryskova, Lenka
Piler, Pavel
Klanova, Jana
Jensen, Tina Kold
Rambaud, Loic
Riou, Margaux
Lamoree, Marja
Kolossa-Gehring, Marike
Vogel, Nina
Weber, Till
Goen, Thomas
Gabriel, Catherine
Sarigiannis, Dimosthenis A.
Sakhi, Amrit Kaur
Haug, Line Smastuen
Murinova, Lubica Palkovicova
Fabelova, Lucia
Tratnik, Janja Snoj
Mazej, Darja
Melymuk, Lisa
[J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2023, 247
[2] Current exposure to phthalates and DINCH in European children and adolescents - Results from the HBM4EU Aligned Studies 2014 to 2021
Vogel, Nina
Schmidt, Phillipp
Lange, Rosa
Gerofke, Antje
Sakhi, Amrit K.
Haug, Line S.
Jensen, Tina Kold
Frederiksen, Hanne
Szigeti, Tamas
Csako, Zsofia
Murinova, Lubica Palkovicova
Sidlovska, Miroslava
Janasik, Beata
Wasowicz, Wojciech
Tratnik, Janja Snoj
Mazej, Darja
Gabriel, Catherine
Karakitsios, Spyros
Barbonem, Fabio
Rosolen, Valentina
Rambaud, Loic
Riou, Margaux
Murawski, Aline
Leseman, Daan
Koppen, Gudrun
Covaci, Adrian
Lignell, Sanna
Lindroos, Anna Karin
Zvonar, Martin
Andryskova, Lenka
Fabelova, Lucia
Richterova, Denisa
Horvatj, Milena
Kosjekj, Tina
Sarigiannis, Denis
Maroulis, Marios
Pedraza-Diaz, Susana
Canas, Ana
Verheyen, Veerle J.
Bastiaensen, Michiel
Gilles, Liese
Schoeters, Greet
Esteban-Lopez, Marta
Castano, Argelia
Govarts, Eva
Kochx, Holger M.
Kolossa-Gehring, Marike
[J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2023, 249
[3] PFAS levels and determinants of variability in exposure in European teenagers - Results from the HBM4EU aligned studies (2014-2021)
Richterova, D.
Govarts, E.
Fabelova, L.
Rausova, K.
Martin, L. Rodriguez
Gilles, L.
Remy, S.
Colles, A.
Rambaud, L.
Riou, M.
Gabriel, C.
Sarigiannis, D.
Pedraza-Diaz, S.
Ramos, J. J.
Kosjek, T.
Tratnik, J. Snoj
Lignell, S.
Gyllenhammar, I
Thomsen, C.
Haug, L. S.
Kolossa-Gehring, M.
Vogel, N.
Franken, C.
Vanlarebeke, N.
Bruckers, L.
Stewart, L.
Sepai, O.
Schoeters, G.
Uhl, M.
Castano, A.
Lopez, M. Esteban
Goeen, T.
Murinova, L' Palkovicova
[J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2023, 247
[4] Glyphosate and AMPA in Human Urine of HBM4EU Aligned Studies: Part A Children
Buekers, Jurgen
Remy, Sylvie
Bessems, Jos
Govarts, Eva
Rambaud, Loic
Riou, Margaux
Tratnik, Janja Snoj
Stajnko, Anja
Katsonouri, Andromachi
Makris, Konstantinos C.
De Decker, Annelies
Morrens, Bert
Vogel, Nina
Kolossa-Gehring, Marike
Esteban-Lopez, Marta
Castano, Argelia
Andersen, Helle Raun
Schoeters, Greet
[J]. TOXICS, 2022, 10 (08)
[5] Determinants of exposure to acrylamide in European children and adults based on urinary biomarkers: results from the "European Human Biomonitoring Initiative" HBM4EU participating studies
F. Fernandez, Sandra
Poteser, Michael
Govarts, Eva
Pardo, Olga
Coscolla, Clara
Schettgen, Thomas
Vogel, Nina
Weber, Till
Murawski, Aline
Kolossa-Gehring, Marike
Ruether, Maria
Schmidt, Phillipp
Namorado, Sonia
Van Nieuwenhuyse, An
Appenzeller, Brice
Olafsdottir, Kristin
Halldorsson, Thorhallur I.
Haug, Line S.
Thomsen, Cathrine
Barbone, Fabio
Mariuz, Marika
Rosolen, Valentina
Rambaud, Loic
Riou, Margaux
Goeen, Thomas
Nuebler, Stefanie
Schaefer, Moritz
Zarrabi, Karin H. A.
Sepai, Ovnair
Martin, Laura Rodriguez
Schoeters, Greet
Gilles, Liese
Leander, Karin
Moshammer, Hanns
Akesson, Agneta
Federica, Laguzzi
[J]. SCIENTIFIC REPORTS, 2023, 13 (01):
[6] Determinants of exposure to acrylamide in European children and adults based on urinary biomarkers: results from the “European Human Biomonitoring Initiative” HBM4EU participating studies
Sandra F. Fernández
Michael Poteser
Eva Govarts
Olga Pardo
Clara Coscollà
Thomas Schettgen
Nina Vogel
Till Weber
Aline Murawski
Marike Kolossa-Gehring
Maria Rüther
Phillipp Schmidt
Sónia Namorado
An Van Nieuwenhuyse
Brice Appenzeller
Kristín Ólafsdóttir
Thorhallur I. Halldorsson
Line S. Haug
Cathrine Thomsen
Fabio Barbone
Marika Mariuz
Valentina Rosolen
Loïc Rambaud
Margaux Riou
Thomas Göen
Stefanie Nübler
Moritz Schäfer
Karin H. A. Zarrabi
Ovnair Sepai
Laura Rodriguez Martin
Greet Schoeters
Liese Gilles
Karin Leander
Hanns Moshammer
Agneta Akesson
Federica Laguzzi
[J]. Scientific Reports, 13 (1)
[7] Concurrent Assessment of Phthalates/HEXAMOLL® DINCH Exposure and Wechsler Intelligence Scale for Children Performance in Three European Cohorts of the HBM4EU Aligned Studies
Rosolen, Valentina
Giordani, Elisa
Mariuz, Marika
Parpinel, Maria
Ronfani, Luca
Brumatti, Liza Vecchi
Bin, Maura
Calamandrei, Gemma
Mustieles, Vicente
Gilles, Liese
Govarts, Eva
Baken, Kirsten
Martin, Laura Rodriguez
Schoeters, Greet
Sepai, Ovnair
Sovcikova, Eva
Fabelova, Lucia
Sidlovska, Miroslava
Kolena, Branislav
Jensen, Tina Kold
Frederiksen, Hanne
Kolossa-Gehring, Marike
Lange, Rosa
Apel, Petra
Castano, Argelia
Esteban Lopez, Marta
Jacobs, Griet
Voorspoels, Stefan
Jurdakova, Helena
Gorova, Renata
Barbone, Fabio
[J]. TOXICS, 2022, 10 (09)
[8] PFAS and Phthalate/DINCH Exposure in Association with Age at Menarche in Teenagers of the HBM4EU Aligned Studies
Cox, Bianca
Wauters, Natasha
Rodriguez-Carrillo, Andrea
Portengen, Lutzen
Gerofke, Antje
Kolossa-Gehring, Marike
Lignell, Sanna
Lindroos, Anna Karin
Fabelova, Lucia
Murinova, Lubica Palkovicova
Desalegn, Anteneh
Iszatt, Nina
Schillemans, Tessa
Akesson, Agneta
Colles, Ann
Den Hond, Elly
Koppen, Gudrun
Van Larebeke, Nicolas
Schoeters, Greet
Govarts, Eva
Remy, Sylvie
[J]. TOXICS, 2023, 11 (08)
[9] Association of exposure to perfluoroalkyl substances (PFAS) and phthalates with thyroid hormones in adolescents from HBM4EU aligned studies
Rodriguez-Carrillo, Andrea
Salamanca-Fernandez, Elena
den Hond, Elly
Verheyen, Veerle J.
Fabelova, Lucia
Murinova, Lubica Palkovicova
Pedraza-Diaz, Susana
Castano, Argelia
Vicente Garcia-Lario, Jose
Remy, Sylvie
Govarts, Eva
Schoeters, Greet
Olea, Nicolas
Freire, Carmen
Fernandez, Mariana F.
[J]. ENVIRONMENTAL RESEARCH, 2023, 237
[10] Exposure assessment of total DON in urine of Portuguese adult population under the HBM4EU aligned studies
Alvito, P. C.
Silva, M. J.
Viegas, S.
Vasco, E.
Martins, C.
Assuncao, R.
Silva, S.
Gilles, L.
Govarts, E.
Schoeters, G.
Namorado, S.
[J]. TOXICOLOGY LETTERS, 2022, 368 : S281 - S281

← 1 2 3 4 5 →