HEART-MUSCLE CONTRACTION OSCILLATION

被引:5
|
作者
KARREMAN, G [1 ]
PROOD, C [1 ]
机构
[1] UNIV PENN,SCH VET MED,DEPT ANIM BIOL,PHILADELPHIA,PA 19104
来源
关键词
MATHEMATICAL MODEL; HEARTBEAT; MUSCLE RELAXATION OSCILLATION; LIMIT CYCLE;
D O I
10.1016/0020-7101(94)01035-Y
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
van der Pol developed a mathematical model for self-sustained radio oscillations described by his non-linear differential equation D(2)X + epsilon(X(2) - 1)DX + X = 0 in which X is a function of time T and D/DT the differential operator to T. For epsilon = 0, this is the differential equation for the harmonic oscillator which has sinusoidal solutions. For epsilon not equal 0 the equation is non-linear, If epsilon > 1 van der Pol coined the name relaxation oscillations for its solutions, These are nonlinear and quite different from simple sinusoidal oscillations. They are mathematical models for many physical and biological phenomena. van der Pol suggested that his equation is also a model for the heartbeat, However, biomedical oscillations, including the heartbeat, have a threshold which the mathematical model described by van der Pol's equation does not possess. It has, in addition to an unstable origin, only a stable limit cycle of Poincare. In this paper, van der Pol's equation is extended in such a way that it has in addition to a stable origin and a stable limit cycle, an unstable limit cycle. Because it possesses such an unstable limit cycle, the extension obtained is a mathematical model for a threshold oscillation, It is also shown that an asymmetric analogy of the extended equation is a mathematical model for an isometric contraction of the mammalian cardiac muscle.
引用
收藏
页码:49 / 53
页数:5
相关论文
共 50 条
  • [1] SIMULATION OF HEART-MUSCLE CONTRACTION
    SAGAWA, K
    NAKAYAMA, K
    SIMULATION, 1976, 27 (03) : C173 - C176
  • [2] CONTRACTION OF DEVELOPING AVIAN HEART-MUSCLE
    GODT, RE
    FOGACA, RTH
    SILVA, IK
    NOSEK, TM
    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY, 1993, 105 (02): : 213 - 218
  • [3] REGULATION OF HEART-MUSCLE CONTRACTION BY SARCOLEMMA
    VANDERWA.JJ
    ALLERS, NJ
    SOUTH AFRICAN MEDICAL JOURNAL, 1973, 47 (22): : 967 - 967
  • [4] ANOMALOUS CONTRACTION OF ISCHEMIC HEART-MUSCLE
    TROMBITAS, K
    ROTH, E
    TOROK, B
    JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY, 1984, 5 (02) : 231 - 231
  • [5] ACTION POTENTIAL AND CONTRACTION OF HEART-MUSCLE
    FOZZARD, HA
    GIBBONS, WR
    AMERICAN JOURNAL OF CARDIOLOGY, 1973, 31 (02): : 182 - 192
  • [6] METABOLIC CONTROL OF HEART-MUSCLE CONTRACTION
    SMIRNOV, VN
    SAKS, VA
    ROZENSHTRAUKH, LV
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1979, 11 : 58 - 58
  • [7] Heart muscle contraction oscillation
    Int J Biomed Comput, 1 (49):
  • [8] THE THEORY OF REGULATION OF CONTRACTION FORCE OF THE HEART-MUSCLE
    MARKHASIN, VS
    MILSTEIN, GN
    SOLOVYEVA, OE
    BIOFIZIKA, 1985, 30 (02): : 322 - 327
  • [9] TOWARD A SARCOMERE BASIS FOR HEART-MUSCLE CONTRACTION
    VANKAAM, FAM
    DEBEER, EL
    SCHIERECK, P
    EXPERIENTIA, 1986, 42 (11-12): : 1308 - 1308
  • [10] EXCITATION-CONTRACTION COUPLING IN HEART-MUSCLE
    LEDERER, WJ
    CANNELL, MB
    COHEN, NM
    BERLIN, JR
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 1989, 89 (02) : 115 - 119