SQUAMOUS CARCINOMA OF ORAL TONGUE - PROGNOSTIC-SIGNIFICANCE OF FLOW-CYTOMETRIC DNA CONTENT

被引：0
|
作者：
GOMEZ, R
ELNAGGAR, AK
BYERS, RM
GARNSEY, L
LUNA, MA
BATSAKIS, JG
机构：
[1] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT PATHOL,BOX 85,1515 HOLCOMBE BLVD,HOUSTON,TX 77030
[2] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT HEAD & NECK SURG,HOUSTON,TX 77030
[3] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT BIOMATH,HOUSTON,TX 77030
来源：
MODERN PATHOLOGY | 1992年 / 5卷 / 02期
关键词：
SQUAMOUS CARCINOMA; ORAL TONGUE; FLOW CYTOMETRY; DNA CONTENT;
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Thirty-eight squamous carcinomas of the mobile tongue were flow cytometrically analyzed for their DNA content, and the results correlated with clinicopathologic parameters and patient survival. Tumor size (p = 0.01), depth of invasion (p = 0.05), histologic differentiation (p = 0.03), ploidy pattern (p = 0.01), and S-phase (p = 0.001) showed significant correlation with patients' clinical outcomes in univariate analyses. A multifactorial regression analysis of all significant parameters indicated that S-phase percentage and depth of tumor invasion were independent prognostic factors in this cohort.
引用
收藏
页码：141 / 145
页数：5
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