SAPONINS IN THE LEAVES OF BIRCH - HEMOLYTIC DAMMARANE TRITERPENOID ESTERS OF BETULA-PENDULA

被引：15
|
作者：
RICKLING, B [1 ]
GLOMBITZA, KW [1 ]
机构：
[1] UNIV BONN, INST PHARMAZEUT BIOL, NUSSALLEE 6, W-5300 BONN 1, GERMANY
来源：
PLANTA MEDICA | 1993年 / 59卷 / 01期
关键词：
BETULA-PENDULA; BETULACEAE; SAPONINS; DAMMARANE ESTERS; HEMOLYSIS; DIURETIC ACTIVITY;
D O I：
10.1055/s-2006-959609
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three hemolytic dammarane triterpenes, esterified with malonate at C-3 and acetate at C-12, were isolated from the leaves of Betula pendula. Their structures were elucidated by chemical and spectroscopic means. Former reports on the presence of saponins in birch leaf extracts could not be confirmed. The hemolytic activity of the extracts, which was ascribed to saponins, is caused by the dammarane esters instead. A fraction containing a mixture of the dammarane esters did not exhibit diuretic activity when tested p.o. in male Wistar rats.
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页码：76 / 79
页数：4
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