SIMULTANEOUS HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF FURAZOLIDONE AND NIFUROXIME IN DOSAGE FORMS

被引：5
|
作者：
HASSAN, SM
IBRAHIM, FA
HEFNAWY, MM
机构：
[1] Analytical Chemistry Department, Faculty of Pharmacy, University of Mansoura, Mansoura
来源：
ANALYTICAL LETTERS | 1990年 / 23卷 / 04期
关键词：
dosage forms; Furazolidone; HPLC; Nifuroxime;
D O I：
10.1080/00032719008052467
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A reversed-phase high-performance liquid chromatographic method for the simultaneous determination of furazolidone and ifuroxime in vaginal suppositories is described. A lichrosorb R.P. 18 (4 x 250 mm) 5 column μm and a mobile phase consisting of methanol-water-buffer pH 3 (40:55:5) were used. Calibration graphs were rectilinear over the concentration range 1–10 μg/ml [or both drugs. Separation was achieved in 12 min. at a wavelength of 350 nm. The proposed method was applied to suppositories containing. the two species, and the results obtained were accurate and precise. © 1990, Taylor & Francis Group, LLC. All rights reserved.
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页码：599 / 606
页数：8
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