LEPROSY AND CELL-MEDIATED-IMMUNITY

被引：30
|
作者：
KAPLAN, G
COHN, ZA
机构：
[1] The Rockefeller University, NY
来源：
CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 01期
关键词：
D O I：
10.1016/0952-7915(91)90083-D
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The intradermal injection of the purified protein derivative of tuberculin into lepromatous leprosy patients leads to a local cell-mediated immune response and to the extensive destruction of Mycobacterium leprae. This local response also occurs after intradermal injection of recombinant human interleukin-2; when administered over an 8-day period interleukin-2 evokes a systemic cell-mediated immune response and a reduction in the bacillary burden.
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页码：91 / 96
页数：6
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