A review of dehydroepiandrosterone (DHEA)

被引：49
|
作者：
Shealy, CN
机构：
[1] The Shealy Institute, Springfield, 65803, MO
来源：
INTEGRATIVE PHYSIOLOGICAL AND BEHAVIORAL SCIENCE | 1995年 / 30卷 / 04期
关键词：
D O I：
10.1007/BF02691603
中图分类号：
B84 [心理学];
学科分类号：
04 ; 0402 ;
摘要：
Dehydroepiandrosterone (DHEA) is quantitatively the most abundant hormone in humans and mammals, with a wide variety of physiological effects, including major regulatory effects upon the immune system. Two of the most striking aspects of DHEA are a steady decline in DHEA with age and a significant deficiency in DHEA in patients with several major diseases, including cancer, atherosclerosis, and Alzheimer's disease. The hormone is secreted in a non-sulfated (DHEA) and sulfated form (DHEA-S). The two are apparently interchangeable, and it appears likely that its physiological effects are achieved by derivative molecules that have yet to be identified.
引用
收藏
页码：308 / 313
页数：6
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