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Univ Basque Country, Ctr Invest Biomed Enfermedades Hepat & Digest, Donostia Hosp, Dept Gastroenterol, San Sebastian 20010, Guipuzcoa, Spain Univ Basque Country, Ctr Invest Biomed Enfermedades Hepat & Digest, Donostia Hosp, Dept Gastroenterol, San Sebastian 20010, Guipuzcoa, Spain