EFFECTS OF AGING ON THE DIURNAL PATTERN OF WATER-INTAKE IN RATS

被引：18
|
作者：
BURWELL, RD
WHEALIN, J
GALLAGHER, M
机构：
[1] Department of Psychology, University of North Carolina, Chapel Hill, NC 27599-3270, Davie Hall
来源：
BEHAVIORAL AND NEURAL BIOLOGY | 1992年 / 58卷 / 03期
关键词：
D O I：
10.1016/0163-1047(92)90468-J
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group. © 1992 Academic Press, Inc.
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页码：196 / 203
页数：8
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