Lipid Profile in 'Newly Diagnosed' and 'On Treatment' Hypothyroid

Introduction: Primary hypothyroidism is a common disorder affecting a large group of population and is a cause of the secondary hyperlipidemia. The aim of the present study was to assess the relation between the lipid profile and thyroid profile in newly diagnosed hypothyroid, subjects on treatment for hypothyroidism and controls. Materials and Methods: The present study was performed on 150 subjects of both sexes between 11- 78 years of age. The subjects were divided into three groups. First group was Controls (n = 50), second group was 'Newly Diagnosed' hypothyroid (n = 50) and the third group was hypothyroid patients 'On Treatment' (n = 50). T-3, T-4, TSH, Total Cholesterol, High Density Lipoproteins (HDL), Low Density Lipoproteins (LDL) and Triglycerides were estimated. Results: ANOVA was calculated among the three groups. TSH, Total Cholesterol and LDL levels were decreased in "On treatment" group when compared to "Newly diagnosed" group. T-4 was found to be elevated, but T-3 remained low in "On treatment" group. Conclusion: Cholesterol and LDL levels are elevated in hypothyroidism and their levels decreases with treatment but not to the level of euthyroid state.